Begin by preparing the sugar and lemon zest rim for your glass. In a shallow dish, mix granulated sugar with finely grated lemon zest. Moisten the rim of your cocktail glass with a lime wedge or water, then gently dip it into the sugar and lemon zest mixture, ensuring even coverage. Shake off any excess and set aside.
In a cocktail shaker, combine the tequila, limoncello, lime juice, and blueberry syrup.
Add ice and shake the mixture vigorously until well-chilled and thoroughly combined.
Strain the margarita into your prepared glass filled with fresh ice.
Garnish your Blueberry Limoncello Margarita with a skewer of fresh blueberries and a lime wedge.