Begin by rimming a cocktail glass with Tajin. Simply moisten the rim of the glass with a lime wedge and dip it into the Tajin until evenly coated.
In a shaker, add the sliced strawberries and jalapeno slices. Use a muddler to gently muddle the ingredients, releasing their juices and flavors.
Add ice to the shaker, followed by the tequila, Grand Marnier, lime juice, and cream of coconut.
Secure the lid on the shaker and shake vigorously for about 15-20 seconds to chill the mixture and incorporate the ingredients.
Strain the margarita into the prepared cocktail glass over fresh ice.
Garnish with a slice of jalapeno or a strawberry, if desired.